Dose-Exposure for Two Dose Strengths of Nasal Insulin (NasulinTM)These data demonstrated that the original Nasulin concentration (1.0%) and the new concentration (0.7%) revealed proportional dose-dependent increases in insulin exposures.
Dr. Berman commented, The data from these studies provide important information on Nasulin ™s ability to rapidly lower glucose following a meal. With the completion of each study, we gain additional insight into the potential benefits Nasulin could offer to patients with diabetes. The most exciting aspect of these results is the second dose concentration, which will provide subjects in future clinical trials with a wider dose range to individually titrate their insulin needs to maximize glucose reduction without increasing the risk of hypoglycemia. These potential advantages of Nasulin ™s ultra-rapid time-action profile may provide treating physicians and their patients safer alternatives for controlling their diabetes.
Source CPEX Pharmaceuticals