the identification of at least three genes thought to promote longevity; evidence that longevity is highly likely to be inherited from generation to generation; andthe finding that those with exceptional longevity are more likely to have significantly elevated levels of HDL or "good" cholesterol.  

The combination of these factors is believed to play a key role in the ability of these "super agers" to avoid cardiovascular disease, insulin resistance and high blood pressure.  

As the study continues, Einstein researchers are hoping to better understand how protective or harmful genes are activated, or "turned on" or "turned off."  This could lead to drug therapies that regulate gene expression and help people live longer, healthier lives by mimicking the beneficial effects of longevity genes.

Visit SuperAgers for more information on the Longevity Genes Project, profiles of the "super agers," the latest updates on advances in aging-related research at Einstein and links to additional resources and research information.

SOURCE Albert Einstein College of Medicine