For the full-year of 2009, worldwide Alimta sales increased 48 percent to $1.706 billion. U.S. Alimta sales for 2009 were $815.6 million, a 45 percent increase driven by higher demand. Alimta sales outside the U.S. were $890.4 million, a 50 percent increase driven by increased demand, partially offset by the unfavorable impact of foreign exchange rates.

Cialis

Cialis sales for the fourth quarter of 2009 increased 19 percent compared with fourth-quarter 2008 to $439.5 million. U.S. sales of Cialis were $166.2 million in the fourth quarter, a 12 percent increase compared with the fourth quarter of 2008, driven primarily by higher prices. Sales of Cialis outside the U.S. increased 24 percent, to $273.4 million, driven by increased demand, higher prices and the favorable impact of foreign exchange rates.

For the full-year of 2009, worldwide Cialis sales increased 8 percent to $1.559 billion. U.S. Cialis sales for 2009 were $623.3 million, a 16 percent increase driven by higher prices, higher demand and wholesaler buying patterns. Cialis sales outside the U.S. were $935.8 million, a 3 percent increase driven by increased demand and to a lesser extent, increased prices, partially offset by the unfavorable impact of foreign exchange rates.

Gemzar

Gemzar sales totaled $310.5 million in the fourth quarter of 2009, a decrease of 25 percent from the fourth quarter of 2008. Sales in the U.S. increased 3 percent, to $191.3 million, due primarily to higher prices and higher demand, partially offset by wholesaler buying patterns. Sales outside the U.S. decreased 47 percent, to $119.1 million, due to lower demand and lower prices as a result of the entry of generic competition in most major markets.

For the full-year of 2009, worldwide Gemzar sales decreased 21 percent to $1.363 billion. U.S. Gemzar sales for 2009 were $747.4 million, a 2 percent increase driven by higher prices. Gemzar sales outside the U.S. were $615.8 million, a 37 percent decrease driven by lower demand, lower prices and to a lesser extent the unfavorable impact of foreign exchange rates.

Evista

Evista sales were $262.7 million in the fourth quarter of 2009, a 2 percent decrease compared with the fourth quarter of 2008. U.S. sales of Evista decreased 2 percent to $175.9 million, as a result of lower demand, partially offset by higher prices. Sales outside the U.S. decreased 2 percent to $86.8 million, driven by lower prices and, to a lesser extent, lower demand, partially offset by the favorable impact of foreign exchange rates.

For the full-year of 2009, worldwide Evista sales decreased 4 percent to $1.030 billion. U.S. Evista sales for 2009 were $682.2 million, a 3 percent decrease driven by lower demand, partially offset by higher prices. Evista sales outside the U.S. were $348.1 million, a 7 percent decrease driven by decreased demand and, to a lesser extent, lower prices.

Humulin

Worldwide Humulin sales increased 4 percent in the fourth quarter of 2009, to $273.0 million. U.S. sales increased 1 percent to $102.5 million. Sales outside the U.S. increased 6 percent, to $170.5 million, driven by increased demand and the favorable impact of foreign exchange rates, partially offset by lower prices.

For the full-year of 2009, worldwide Humulin sales decreased 4 percent to $1.022 billion. U.S. Humulin sales for 2009 were $402.4 million, a 6 percent increase driven by higher prices, partially offset by lower demand. Humulin sales outside the U.S. were $619.6 million, a 9 percent decrease driven by the unfavorable impact of foreign exchange rates and, to a lesser extent, lower prices, partially offset by increased demand.

Forteo

Fourth-quarter sales of Forteo were $212.8 million, a 9 percent increase compared with the fourth quarter of 2008. U.S. sales of Forteo increased 3 percent, to $129.4 million, driven by higher prices, partially offset by lower demand. Sales outside the U.S. increased 20 percent, to $83.5 million, due to higher prices and the favorable impact of foreign exchange rates.

For the full-year of 2009, worldwide Forteo sales increased 5 percent to $816.7 million. U.S. Forteo sales for 2009 were $518.3 million, a 6 percent increase driven by higher prices, partially offset by lower demand. Forteo sales outside the U.S. were $298.4 million, a 3 percent increase driven by increased demand and increased prices, partially offset by the unfavorable impact of foreign exchange rates.

Strattera

During the fourth quarter of 2009, Strattera generated $162.2 million of sales, an increase of 10 percent compared with the fourth quarter of 2008. U.S. sales increased 5 percent to $117.5 million, due to higher prices. Sales outside the U.S. increased 26 percent, to $44.7 million, driven by increased demand, the favorable impact of foreign exchange rates and higher prices.

For the full-year of 2009, worldwide Strattera sales increased 5 percent to $609.4 million. U.S. Strattera sales for 2009 were $445.6 million, a 2 percent increase driven by higher prices, partially offset by lower demand. Strattera sales outside the U.S. were $163.7 million, a 15 percent increase driven by increased demand and increased prices, partially offset by the unfavorable impact of foreign exchange rates.

Byetta

Lilly recognizes in revenue its 50 percent share of Byetta's gross margin in the U.S., 100 percent of Byetta sales outside the U.S., and its sales of Byetta pen delivery devices to its partner, Amylin Pharmaceuticals. For the fourth quarter, Lilly recognized total revenue of $120.5 million for Byetta, an increase of 17 percent.

Worldwide sales of Byetta were $203.6 million in the fourth quarter of 2009, a 9 percent increase compared with the fourth quarter of 2008, driven by growth in international markets. U.S. sales of Byetta increased 1 percent to $163.7 million compared with the fourth quarter of 2008, while sales of Byetta outside the U.S. were $39.9 million.

For the full-year of 2009, worldwide Byetta sales increased 6 percent to $796.5 million. U.S. Byetta sales for 2009 decreased 2 percent to $667.6 million, while sales outside the U.S. increased 77 percent to $128.9 million. For the full-year of 2009, Lilly recognized revenue totaling $448.5 million, representing a 13 percent increase compared with 2008.

Erbitux

Lilly recognizes net royalties received from its Erbitux collaboration partners and revenue from manufactured product sold to these partners. For the fourth quarter, Lilly recognized total revenue of $95.0 million for Erbitux. For the full-year of 2009, Lilly recognized total Erbitux revenue of $390.8 million.

Effient?„?

Worldwide Effient sales were $3.8 million in the fourth quarter of 2009. U.S. Effient sales were $1.4 million. Sales outside the U.S. were $2.4 million. The product is in the early phases of launch in both the U.S. and Europe. Lilly and its partner, Daiichi Sankyo, continue to make good progress in gaining reimbursement and access for the product.

For the full-year of 2009, worldwide Effient sales were $27.0 million. U.S. Effient sales for 2009 were $22.5 million. Sales outside the U.S. were $4.5 million.

Animal Health

Worldwide sales of animal health products in the fourth quarter of 2009 were $353.1 million, an increase of 8 percent compared with the fourth quarter of 2008. U.S. sales grew 1 percent, to $187.7 million, primarily due to higher prices and increased sales of Comfortis, partially offset by lower demand of other animal health products. Sales outside the U.S. increased 17 percent, to $165.5 million, driven primarily by increased demand and, to a lesser extent, the favorable impact of foreign exchange rates.

For the full-year of 2009, worldwide animal health sales increased 10 percent to $1.207 billion. U.S. animal health sales for 2009 were $672.2 million, a 25 percent increase primarily due to the inclusion of sales from the Posilac?® acquisition completed in October, 2008. Animal health sales outside the U.S. were $535.0 million, a 4 percent decrease driven by the unfavorable impact of foreign exchange rates.

2010 Financial Guidance

The company reconfirmed the 2010 financial guidance that it originally provided at its investment community meeting in December, 2009. Excluding the potential impact of health care reform in the U.S., the company expects 2010 earnings per share of $4.65 to $4.85 on both a reported and a non-GAAP basis.

Numbers in the 2009 column do not add due to rounding.

The company expects volume-driven revenue growth in the high-single digits, driven primarily by Alimta, Cymbalta, Humalog, Cialis, Effient and the exenatide franchise.

The company anticipates that gross margin as a percent of revenue will be flat to declining. Excluding the effect of foreign exchange rates on international inventories sold, the company expects gross margin as a percent of revenue to increase.

Marketing, selling and administrative expenses are projected to grow in the low- to mid-single digits while research and development expenses are projected to grow in the low-double digits.

Other income is expected to be a net expense of between $150.0 and $200.0 million, and the tax rate is expected to be approximately 22 percent.

Cash flows are expected to be sufficient to fund capital expenditures of approximately $1.0 billion, anticipated business development activity and the company's dividend.

SOURCE Eli Lilly and Company