Prior to the XF Extracellular Analyzer, scientists relied on 50 year old Clark electrode technology for measuring cell metabolism, a time-consuming technique that provides nominal basic information. Now in minutes, the XF Analyzer measures oxygen consumption--an indicator of mitochondrial respiration--as well as extracellular acidification, a product of glycolysis (sugar burning). With just a small number of cells, investigators can measure the effects of up to four compounds on cellular metabolism, determining the basal oxygen consumption and glycolysis rates; respiratory capacity; mitochondrial dysfunction; fatty acid oxidation, glucose, fatty acid, and amino acid metabolism; uncoupling; ATP turnover; and cell signaling in primary, adherent, tumor and suspension cells, islets, and isolated mitochondria. All important information needed when developing new drugs.

One of TheScientist's judge's Dr. H. Steven Wiley, summed up the XF Analyzer's significance stating: "I want one!'

SOURCE Seahorse Bioscience, Inc.